This Regulation covers the procedures and principles related to the self-checks conducted by food business operators, as well as the specific hygiene requirements and the responsibilities of food business operators producing unprocessed and processed food of animal origin. This Regulation does not apply to food containing both products of plant origin and processed products of animal origin. However, processed products of animal origin used to prepare such food shall be obtained and handled in accordance with the requirements stated in this Regulation. The Regulation repeals the Specific Hygiene Rules for Foods of Animal Origin, which was published in the Official Gazette dated 27 December 2011 and numbered 28155. The main amendments include following issues: The requirement to apply a special health mark has been abolished; The collagen and gelatine production process, for gelatine and collagen are regulated; Specific hygiene requirements have been established for some highly refined products (such as chondroitin sulphate, hyaluronic acid, other hydrolysed cartilage products, chitosan, glucosamine, rennet, amino acids permitted as food additives); Regulations have been made regarding special requirements for echinoderms by excluding the classified production areas of echinoderms that do not filter feed from the relevant provisions; An exemption from the obligation to cool carcasses to 7 °C in the slaughterhouse before transport has been provided and additional rules have…