Health Canada's Food Directorate completed a premarket assessment of a food additive submission seeking authorization for the use of silicon dioxide as an anticaking agent in nutrient pre-mixes for use in infant formula. The outcome of the premarket assessment supports authorizing silicon dioxide for use as an anticaking agent in nutrient pre-mixes for use in infant formula at a maximum level of use of Good Manufacturing Practice, with the silicon dioxide residue in the formula as consumed not to exceed 10 ppm. Consequently, Health Canada has extended the use of silicon dioxide as described in the Notice by modifying the List of Permitted Anticaking Agents, effective 29 October 2026. The purpose of the information document is to publicly announce the Department's decision in this regard and to provide the appropriate contact information for those wishing to submit an inquiry or new scientific information relevant to the safety of this food additive.